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PhD project position in the UK: The role of dll4 in haematopoietic stem cell
Applications are invited for a 4-year PhD Studentship within the Midlands Integrative Biosciences Training Partnership (MIBTP), fully funded by the BBSRC starting October 2020
Haematopoietic stem cells (HSCs) are generated during embryonic development and are responsible for the production and maintenance of all the blood lineages throughout adult life. They arise from the haemogenic endothelium (HE), a specialized subset of endothelial cells located in the floor of the main embryonic artery, the dorsal aorta. One of the bottlenecks in the production of HSCs in vitro for substitution therapies is to determine the right conditions that mimic the embryo microenvironment and induce a HE-like intermediate that can differentiate into HSCs. The Monteiro lab is interested in understanding how endothelial and blood stem cells grow and differentiate during embryonic development and how lineage fate decisions lead to the formation of HSCs from the HE.
More information here.
Three exciting positions in IKAN Biotech, Spain (https://www.ikanbiotech.com/)
Head of Zebrafish Cancer Laboratory (PhD required)
Genetic Research Assistant (MSc required)
Zebrafish Research Assistant (MSc required)
Deadline: 29 November 2019
Postdoctoral position in Neural Stem Cells/iPSCs
A Postdoctoral position is available at the Department of Physiology of the University of Lausanne (Switzerland) to study neuronal differentiation from human induced pluripotent stem cells (iPSCs) to model the sleep disorder narcolepsy.
The project will aim at characterizing hypothalamic neurons derived from iPSCs of narcolepsy patients and control subjects. It includes generation of iPSCs from fibroblasts or PBMCs, hypothalamic neuronal differentiation, transcriptome and proteomic analysis, in-vitro electrophysiology and basic immunology.
At least 60% of the working time will be dedicated to personal research
Candidates should have a PhD in neurobiology, molecular biology, cell biology or related fields. The successful candidate must have a strong background in working with human stem and iPSC cells with demonstrated expertise in generation of human iPSCs and human neuronal differentiation. Additional expertise in cell biology, molecular biology, neurobiology, fluorescence microscopy, and flow cytometry and electrophysiology is preferred.
Approximate Salary $80,000
Duration: 2 years
Host lab: http://unil.ch/physiologie/mehdi-tafti